Endocrine Abstracts

‘European Young Endocrine Scientists’ (EYES), founded in 2011, is a committee under the patronage of the European Society of Endocrinology (ESE). Our primary goal is to increase the mutual exchange of ideas and knowledge between early career researchers (ECR’s) across Europe, in both basic and clinical endocrinology. EYES enables ECR’s from all ESE member societies to actively contribute to the society’s activities and help them fully develop into the ...

Background: Therapeutic activation of thermogenic brown adipose tissue (BAT) is a potential strategy to prevent obesity and metabolic disease in humans. However, it is now recognised that rodent studies examining BAT physiology are carried out at sub-thermoneutral temperatures (e.g. ~20°C), and are not translationally relevant to humans as BAT is ‘hyperactive’. Therefore, the aim of this study was to determine the effect of common regulators of BAT metabolism wh...

Background: Current NICE guidance states that insulin pump therapy (CSII) can be considered in Type 1 diabetes (T1DM) patients who suffer disabling hypoglycaemia in an attempt to reach glycaemic control or whose HbA1C remains high (>69 mmol/l) despite careful management on multiple daily injections (MDI).Aims: Our aims were to determine impact of CSII therapy on glycaemic control, BMI, incidence of severe hypoglycaemia and episodes of diabetic ketoac...